The Times Square Hotel's bar was called . . . the American. I don't think it's still around. Wikipedia:

In the early 1970s, the hotel became home to the mentally ill and troubled Vietnam War veterans, and New York City subsequently placed welfare recipients there After a period of deterioration, Covenant House acquired the building in 1984 as real estate investment.

Common Ground, offering affordable housing for working professionals and the formerly homeless, some of whom live with HIV/AIDS, mental illness, or physical disabilities, acquired the building in 1991 as its flagship supportive housing residence.

It wasn't an interesting building when it was built, but if nothing had changed since its 1922 debut, it would be an object of boundless fascination.